A.382 Presurgical administration of intra-articular morphine fails to produce postoperative analgesia in humans

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منابع مشابه

Intra-articular morphine and clonidine produce comparable analgesia but the combination is not more effective.

Both intra-articular morphine and clonidine produce analgesia. This study was designed to compare the analgesic effects of the two drugs, used separately and in combination. We studied 90 patients undergoing arthroscopy of the knee under general anaesthesia. Patients were allocated randomly to receive 20 ml of intra-articular isotonic saline solution containing morphine 2 mg, clonidine 150 micr...

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Reconstruction of the anterior cruciate ligament: comparison of analgesia using intrathecal morphine, intra-articular morphine and intra-articular levobupivacaine☆

OBJECTIVE To compare the analgesic effect of intra-articular administration of morphine and levobupivacaine (separately or in combination) with intrathecal administration of morphine in patients undergoing anterior cruciate ligament (ACL) reconstruction using autologous grafts from the patellar tendon. METHODS This was a retrospective analysis on data gathered from the medical files of 60 pat...

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Intra-articular morphine versus bupivacaine for postoperative pain management.

The purpose of this study was to determine whether morphine would be as effective as bupivacaine for postoperative pain control after knee arthroscopy with no worsening of the side effect profile. Eighty-two patients who underwent partial meniscectomy, chondral debridement, or both were prospectively randomized to receive 10 mg of morphine (10-cc volume) or 10 cc of .5% bupivacaine immediately ...

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Postoperative spinal analgesia with morphine.

Patients with pain after operation received morphine hydrochloride intrathecally in doses of 0.02 mg kg-1 (n = 30) and 0.2 mg kg-1 (n = 30). The high-dose group showed slightly longer-lasting and more potent analgesia than the low-dose group. Sedation, decreases in heart rate and systolic arterial pressure, oliguria, nausea and urinary retention were more frequent in the high-dose group. Two pa...

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Effect of Spinal and Systemic Clonidine Administration on the Postoperative Analgesia in Morphine-dependent and Naive Rats

Post operative pain and its control remains one of the most important issues in the field of surgery and health care system. Formalin test has been used as a method for assessing pain and analgesia in rats. Systemic and spinally administered clonidine, an ?2-adrenergic agonist, is proved to enhance postoperative analgesia. It has also been shown that morphine-dependent rats experience more chr...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 1996

ISSN: 0007-0912

DOI: 10.1016/s0007-0912(18)31237-6